MCML Researchers With Seven Papers at AAAI 2025

Federated Learning (FL) is a distributed machine learning (ML) paradigm, in which multiple clients collaboratively train ML models without centralizing their local data. Similar to conventional ML pipelines, the client local optimization and server aggregation procedure in FL are sensitive to the hyperparameter (HP) selection. Despite extensive research on tuning HPs for centralized ML, these methods yield suboptimal results when employed in FL. This is mainly because their ’training-after-tuning’ framework is unsuitable for FL with limited client computation power. While some approaches have been proposed for HP-Tuning in FL, they are limited to the HPs for client local updates. In this work, we propose a novel HP-tuning algorithm, called Federated Population-based Hyperparameter Tuning (FedPop), to address this vital yet challenging problem. FedPop employs population-based evolutionary algorithms to optimize the HPs, which accommodates various HP types at both the client and server sides. Compared with prior tuning methods, FedPop employs an online ’tuning-while-training’ framework, offering computational efficiency and enabling the exploration of a broader HP search space. Our empirical validation on the common FL benchmarks and complex real-world FL datasets, including full-sized Non-IID ImageNet-1K, demonstrates the effectiveness of the proposed method, which substantially outperforms the concurrent state-of-the-art HP-tuning methods in FL.

In this work we propose a novel method for unsupervised controllable video generation. Once trained on a dataset of unannotated videos, at inference our model is capable of both composing scenes of predefined object parts and animating them in a plausible and controlled way. This is achieved by conditioning video generation on a randomly selected subset of local pre-trained self-supervised features during training. We call our model CAGE for visual Composition and Animation for video GEneration. We conduct a series of experiments to demonstrate capabilities of CAGE in various settings.

Current discriminative depth estimation methods often produce blurry artifacts, while generative approaches suffer from slow sampling due to curvatures in the noise-to-depth transport. Our method addresses these challenges by framing depth estimation as a direct transport between image and depth distributions. We are the first to explore flow matching in this field, and we demonstrate that its interpolation trajectories enhance both training and sampling efficiency while preserving high performance. While generative models typically require extensive training data, we mitigate this dependency by integrating external knowledge from a pre-trained image diffusion model, enabling effective transfer even across differing objectives. To further boost our model performance, we employ synthetic data and utilize image-depth pairs generated by a discriminative model on an in-the-wild image dataset. As a generative model, our model can reliably estimate depth confidence, which provides an additional advantage. Our approach achieves competitive zero-shot performance on standard benchmarks of complex natural scenes while improving sampling efficiency and only requiring minimal synthetic data for training.

Leveraging the vast genetic diversity within microbiomes offers unparalleled insights into complex phenotypes, yet the task of accurately predicting and understanding such traits from genomic data remains challenging. We propose a framework taking advantage of existing large models for gene vectorization to predict habitat specificity from entire microbial genome sequences. Based on our model, we develop attribution techniques to elucidate gene interaction effects that drive microbial adaptation to diverse environments. We train and validate our approach on a large dataset of high quality microbiome genomes from different habitats. We not only demonstrate solid predictive performance, but also how sequence-level information of entire genomes allows us to identify gene associations underlying complex phenotypes. Our attribution recovers known important interaction networks and proposes new candidates for experimental follow up.

Accurately describing images with text is a foundation of explainable AI. Vision-Language Models (VLMs) like CLIP have recently addressed this by aligning images and texts in a shared embedding space, expressing semantic similarities between vision and language embeddings. VLM classification can be improved with descriptions generated by Large Language Models (LLMs). However, it is difficult to determine the contribution of actual description semantics, as the performance gain may also stem from a semantic-agnostic ensembling effect, where multiple modified text prompts act as a noisy test-time augmentation for the original one. We propose an alternative evaluation scenario to decide if a performance boost of LLM-generated descriptions is caused by such a noise augmentation effect or rather by genuine description semantics. The proposed scenario avoids noisy test-time augmentation and ensures that genuine, distinctive descriptions cause the performance boost. Furthermore, we propose a training-free method for selecting discriminative descriptions that work independently of classname-ensembling effects. Our approach identifies descriptions that effectively differentiate classes within a local CLIP label neighborhood, improving classification accuracy across seven datasets. Additionally, we provide insights into the explainability of description-based image classification with VLMs.

Medical multimodal large language models (MLLMs) are becoming an instrumental part of healthcare systems, assisting medical personnel with decision making and results analysis. Models for radiology report generation are able to interpret medical imagery, thus reducing the workload of radiologists. As medical data is scarce and protected by privacy regulations, medical MLLMs represent valuable intellectual property. However, these assets are potentially vulnerable to model stealing, where attackers aim to replicate their functionality via black-box access. So far, model stealing for the medical domain has focused on classification; however, existing attacks are not effective against MLLMs. In this paper, we introduce Adversarial Domain Alignment (ADA-STEAL), the first stealing attack against medical MLLMs. ADA-STEAL relies on natural images, which are public and widely available, as opposed to their medical counterparts. We show that data augmentation with adversarial noise is sufficient to overcome the data distribution gap between natural images and the domain-specific distribution of the victim MLLM. Experiments on the IU X-RAY and MIMIC-CXR radiology datasets demonstrate that Adversarial Domain Alignment enables attackers to steal the medical MLLM without any access to medical data.

LLM-based autonomous agents often fail to execute complex web tasks that require dynamic interaction due to the inherent uncertainty and complexity of these environments. Existing LLM-based web agents typically rely on rigid, expert-designed policies specific to certain states and actions, which lack the flexibility and generalizability needed to adapt to unseen tasks. In contrast, humans excel by exploring unknowns, continuously adapting strategies, and resolving ambiguities through exploration. To emulate human-like adaptability, web agents need strategic exploration and complex decision-making. Monte Carlo Tree Search (MCTS) is well-suited for this, but classical MCTS struggles with vast action spaces, unpredictable state transitions, and incomplete information in web tasks. In light of this, we develop WebPilot, a multi-agent system with a dual optimization strategy that improves MCTS to better handle complex web environments. Specifically, the Global Optimization phase involves generating a high-level plan by breaking down tasks into manageable subtasks and continuously refining this plan, thereby focusing the search process and mitigating the challenges posed by vast action spaces in classical MCTS. Subsequently, the Local Optimization phase executes each subtask using a tailored MCTS designed for complex environments, effectively addressing uncertainties and managing incomplete information. Experimental results on WebArena and MiniWoB++ demonstrate the effectiveness of WebPilot. Notably, on WebArena, WebPilot achieves SOTA performance with GPT-4, achieving a 93% relative increase in success rate over the concurrent tree search-based method. WebPilot marks a significant advancement in general autonomous agent capabilities, paving the way for more advanced and reliable decision-making in practical environments.