24.01.2025

Teaser image to How to analyze millions of individual cells

How to Analyze Millions of Individual Cells

TUM News Article

Researchers from the Technical University of Munich (TUM) and Helmholtz Munich have tested self-supervised learning as a promising approach for analysing over 20 million individual cells. MCML PI Fabian Theis holds the Chair of Mathematical Modelling of Biological Systems at TUM. Together with his team, he has investigated whether self-supervised learning is better suited to analysing large amounts of data than other methods.

Given the enormous amounts of data generated by advances in single-cell technology, it is important to interpret them efficiently in order to recognise differences between healthy cells and those with diseases such as lung cancer or COVID-19. Self-supervised learning does not require pre-classified data and enables the robust processing of large amounts of data.

The study shows that this method improves performance, especially on transfer tasks and zero-shot predictions. The researchers compare masked learning and contrastive learning and find that masked learning is better suited for large datasets. The results could lead to the development of virtual cells that map the diversity of cells in different datasets and are useful for analysing cell changes in diseases.

24.01.2025


Subscribe to RSS News feed

Related

Link to Reinhard Heckel on Bayerischer Rundfunk

14.02.2025

Reinhard Heckel on Bayerischer Rundfunk

Reinhard Heckel spoke on BR24 about OpenAI's new Munich office, highlighting the city's deeptech scene, talent, and innovation potential.


Link to Benjamin Lange on ZDF heute journal

14.02.2025

Benjamin Lange on ZDF Heute Journal

Benjamin Lange was on heute journal discussing AI in universities. He highlighted that writing is key to thinking and shouldn’t be fully automated.


Link to Gitta Kutyniok on Supporting Companies with the EU’s AI Act

14.02.2025

Gitta Kutyniok on Supporting Companies With the EU’s AI Act

Gitta Kutyniok and her team at LMU are helping companies navigate the challenges of the EU’s AI Act, focusing on practical solutions and innovation.


Link to Improving Business Processes

06.02.2025

Improving Business Processes

Gabriel Marques Tavares, MCML Junior Member and LMU PostDoc, explores Process Mining to optimize workflows and promote data-driven decisions.


Link to Reinhard Heckel Featured on Sat1 Newstime

31.01.2025

Reinhard Heckel Featured on Sat1 Newstime

Reinhard Heckel discussed DeepSeek's potential to create high-quality AI models at low cost.