Research Group Helmut Küchenhoff
Helmut Küchenhoff
Prof. Dr.
Core PI
Helmut Küchenhoff
is the former head of the Statistical Consulting Unit (StaBLab) at LMU Munich, which is known for providing expert statistical guidance to both academic researchers and industries.
His research interests include statistical modeling, measurement error, and misclassification, with a focus on applying statistical techniques to real-world data, including the analysis of COVID-19 data.
Team members @MCML
PhD Students
Henri Funk
→ Group Helmut Küchenhoff
Statistical Consulting Unit (StaBLab)
Johannes Piller
→ Group Helmut Küchenhoff
Statistical Consulting Unit (StaBLab)
Recent News @MCML
Publications @MCML
2026
[33]
H. Funk • C. Gruber • G. Kauermann • H. Küchenhoff • R. Ludwig • M. Mittermeier
Uncertainty-Aware AI Forecasting of European Droughts: The Role of Internal Climate Variability.
EGU 2026 - General Assembly of the European Geosciences Union. Vienna, Austria, May 03-08, 2026. DOI
Uncertainty-Aware AI Forecasting of European Droughts: The Role of Internal Climate Variability.
EGU 2026 - General Assembly of the European Geosciences Union. Vienna, Austria, May 03-08, 2026. DOI
[32]
C. Gruber • H. Funk • M. Mittermeier • H. Küchenhoff • G. Kauerman
Capturing Aleatoric Uncertainty in Climate Models.
Preprint (Apr. 2026). arXiv
Capturing Aleatoric Uncertainty in Climate Models.
Preprint (Apr. 2026). arXiv
[31]
W. H. Hartl • C. Stoppe • Y. Kotani • G. Landoni • A. G. Day • J. Piller • M. Neuberger • A. Bender
Study protocol for the use of propofol in adult intensive care unit patients: a secondary analysis of an extensive international database.
Critical Care Science 38. Mar. 2026. DOI
Study protocol for the use of propofol in adult intensive care unit patients: a secondary analysis of an extensive international database.
Critical Care Science 38. Mar. 2026. DOI
[30]
J. Lonardi • S. Halimeh • S. von Mackensen • L. Kleinlein • J. Fleischer • H. Funk • J. Hölz • J. Holzapfel • S. Juranek • V. Lieftüchter • C. Bidlingmaier • M. Olivieri
HAEMFIX: Impact of Switching From SHL‐FIX to EHL‐FIX in Patients With Haemophilia B.
Haemophilia 32.1. Jan. 2026. DOI
HAEMFIX: Impact of Switching From SHL‐FIX to EHL‐FIX in Patients With Haemophilia B.
Haemophilia 32.1. Jan. 2026. DOI
2025
[29]
S. F. Fischer • J. Zobolas • R. Sonabend • M. Becker • M. Lang • M. Binder • L. Schneider • L. Burk • P. Schratz • B. C. Jaeger • S. A. Lauer • L. A. Kapsner • M. Mücke • Z. Wang • D. Pulatov • K. Ganz • H. Funk • L. Harutyunyan • P. Camilleri • P. Kopper • A. Bender • B. Zhou • N. German • L. Koers • A. Nazarova • B. Bischl
mlr3extralearners: Expanding the mlr3 Ecosystem with Community-Driven Learner Integration.
The Journal of Open Source Software 10.115. Nov. 2025. DOI
mlr3extralearners: Expanding the mlr3 Ecosystem with Community-Driven Learner Integration.
The Journal of Open Source Software 10.115. Nov. 2025. DOI
[28]
S. Wiegrebe • J. Piller • M. Gorski • M. Behr • H. Küchenhoff • I. M. Heid • A. Bender
Multi-state Models For Modeling Disease Histories Based On Longitudinal Data.
Preprint (Sep. 2025). arXiv
Multi-state Models For Modeling Disease Histories Based On Longitudinal Data.
Preprint (Sep. 2025). arXiv
[27]
H. Funk • R. Ludwig • H. Küchenhoff • T. Nagler
Towards more realistic climate model outputs: A multivariate bias correction based on zero-inflated vine copulas.
Journal of the Royal Statistical Society. Series C (Applied Statistics).qlaf044. Aug. 2025. DOI
Towards more realistic climate model outputs: A multivariate bias correction based on zero-inflated vine copulas.
Journal of the Royal Statistical Society. Series C (Applied Statistics).qlaf044. Aug. 2025. DOI
[26]
H. Funk • R. Ludwig • H. Küchenhoff • T. Nagler
Modelling Climate Variables at High Temporal Resolution.
Preprint (Feb. 2025). DOI
Modelling Climate Variables at High Temporal Resolution.
Preprint (Feb. 2025). DOI
[25]
M. Gorski • S. Wiegrebe • R. Burkhardt • M. Behr • H. Küchenhoff • K. J. Stark • C. A. Böger • I. M. Heid
Bias-corrected serum creatinine from UK Biobank electronic medical records generates an important data resource for kidney function trajectories.
Scientific Reports 15.3540. Jan. 2025. DOI
Bias-corrected serum creatinine from UK Biobank electronic medical records generates an important data resource for kidney function trajectories.
Scientific Reports 15.3540. Jan. 2025. DOI
[24]
M. Aleksic • T. Ehring • A. Kunze • Y. Han • H. Funk • L. Wolkenstein
Selective Effects of Eye Movement Desensitization and Reprocessing, Imagery Rescripting and Imaginal Exposure on Voluntary and Involuntary Memory of an Aversive Autobiographical Event.
Preprint (Jan. 2025). DOI
Selective Effects of Eye Movement Desensitization and Reprocessing, Imagery Rescripting and Imaginal Exposure on Voluntary and Involuntary Memory of an Aversive Autobiographical Event.
Preprint (Jan. 2025). DOI
2024
[23]
A. Beyerlein • K. Katz • H. Küchenhoff • W. Hartl
Long-Term Changes in Vaccination Protection Against Severe Courses of COVID-19 by Non-adapted MRNA-Based Vaccines.
Deutsches Ärzteblatt 121.24. Nov. 2024. DOI
Long-Term Changes in Vaccination Protection Against Severe Courses of COVID-19 by Non-adapted MRNA-Based Vaccines.
Deutsches Ärzteblatt 121.24. Nov. 2024. DOI
[22]
C. Janke • R. Rubio-Acero • M. Weigert • C. Reinkemeyer • Y. Khazaei • L. Kleinlein • R. Le Gleut • K. Radon • M. Hannes • F. Picasso • A. E. Lucke • M. Plank • I. C. Kotta • I. Paunovic • A. Zhelyazkova • I. Noreña • S. Winter • M. Hoelscher • A. Wieser • H. Küchenhoff • N. Castelletti • o. b. o. t. ORCHESTRA Working Group
Understanding the Omicron Variant Impact in Healthcare Workers: Insights from the Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf) on Risk Factors for Breakthrough and Reinfections.
Viruses 16.10. Sep. 2024. DOI
Understanding the Omicron Variant Impact in Healthcare Workers: Insights from the Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf) on Risk Factors for Breakthrough and Reinfections.
Viruses 16.10. Sep. 2024. DOI
[21]
C. A. Scholbeck • H. Funk • G. Casalicchio
Algorithm-Agnostic Feature Attributions for Clustering.
xAI 2024 - 2nd World Conference on Explainable Artificial Intelligence. Valletta, Malta, Jul 17-19, 2024. DOI
Algorithm-Agnostic Feature Attributions for Clustering.
xAI 2024 - 2nd World Conference on Explainable Artificial Intelligence. Valletta, Malta, Jul 17-19, 2024. DOI
[20]
J. Piller • H. Küchenhoff • A. Bender
Flexible additive models for multi-event survival analysis.
IWSM 2024 - 38th International Workshop on Statistical Modelling. Durham, UK, Jul 14-19, 2024. PDF
Flexible additive models for multi-event survival analysis.
IWSM 2024 - 38th International Workshop on Statistical Modelling. Durham, UK, Jul 14-19, 2024. PDF
[19]
W. H. Hartl • P. Kopper • L. Xu • L. Heller • M. Mironov • R. Wang • A. G. Day • G. Elke • H. Küchenhoff • A. Bender
Relevance of Protein Intake for Weaning in the Mechanically Ventilated Critically Ill: Analysis of a Large International Database.
Critical Care Medicine 50.3. Mar. 2024. DOI
Relevance of Protein Intake for Weaning in the Mechanically Ventilated Critically Ill: Analysis of a Large International Database.
Critical Care Medicine 50.3. Mar. 2024. DOI
2023
[18]
A. Beyerlein • M. Weigert • K. Katz • H. Küchenhoff • W. Hartl
Langzeitveränderungen des Impfschutzes vor schweren COVID-19-Verläufen.
Deutsches Ärzteblatt 120.51-52. Nov. 2023. DOI
Langzeitveränderungen des Impfschutzes vor schweren COVID-19-Verläufen.
Deutsches Ärzteblatt 120.51-52. Nov. 2023. DOI
[17]
A. Beyerlein • M. Weigert • K. Katz • H. Küchenhoff • W. Hartl
Long-Term Trends in the Protection Against Severe Courses of COVID-19 by Vaccination.
Deutsches Ärzteblatt 120.51-52. Nov. 2023. DOI
Long-Term Trends in the Protection Against Severe Courses of COVID-19 by Vaccination.
Deutsches Ärzteblatt 120.51-52. Nov. 2023. DOI
[16]
D. Wolffram • S. Abbott • M. an der Heiden • S. Funk • F. Günther • D. Hailer • S. Heyder • T. Hotz • J. van de Kassteele • H. Küchenhoff • S. Müller-Hansen • D. Syliqi • A. Ullrich • M. Weigert • M. Schienle • J. Bracher
Collaborative nowcasting of COVID-19 hospitalization incidences in Germany.
PLOS Computational Biology 19.8. Aug. 2023. DOI
Collaborative nowcasting of COVID-19 hospitalization incidences in Germany.
PLOS Computational Biology 19.8. Aug. 2023. DOI
[15]
C. Reinkemeyer • Y. Khazaei • M. Weigert • M. Hannes • R. Le Gleut • M. Plank • S. Winter • I. Norena • T. Meier • L. Xu • R. Rubio-Acero • S. Wiegrebe • T. G. Le Thi • C. Fuchs • K. Radon • I. Paunovic • C. Janke • A. Wieser • H. Küchenhoff • M. Hoelscher • N. Castelletti • K. I. O. Working Grp
The Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf): Risk Factors and Determinants of Immune Response in Healthcare Workers.
Viruses 15.7. Jul. 2023. DOI
The Prospective COVID-19 Post-Immunization Serological Cohort in Munich (KoCo-Impf): Risk Factors and Determinants of Immune Response in Healthcare Workers.
Viruses 15.7. Jul. 2023. DOI
[14]
L. Zumeta-Olaskoaga • M. Weigert • J. Larruskain • E. Bikandi • I. Setuain • J. Lekue • H. Küchenhoff • D.-J. Lee
Prediction of sports injuries in football: a recurrent time-to-event approach using regularized Cox models.
Advances in Statistical Analysis 107. Mar. 2023. DOI
Prediction of sports injuries in football: a recurrent time-to-event approach using regularized Cox models.
Advances in Statistical Analysis 107. Mar. 2023. DOI
2022
[13]
C. Fritz • G. De Nicola • F. Günther • D. Rügamer • M. Rave • M. Schneble • A. Bender • M. Weigert • R. Brinks • A. Hoyer • U. Berger • H. Küchenhoff • G. Kauermann
Challenges in Interpreting Epidemiological Surveillance Data – Experiences from Germany.
Journal of Computational and Graphical Statistics 32.3. Dec. 2022. DOI
Challenges in Interpreting Epidemiological Surveillance Data – Experiences from Germany.
Journal of Computational and Graphical Statistics 32.3. Dec. 2022. DOI
[12]
E. Pretzsch • V. Heinemann • S. Stintzing • A. Bender • S. Chen • J. W. Holch • F. O. Hofmann • H. Ren • F. Böschand • H. Küchenhoff • J. Werner • M. K. Angele
EMT-Related Genes Have No Prognostic Relevance in Metastatic Colorectal Cancer as Opposed to Stage II/III: Analysis of the Randomised, Phase III Trial FIRE-3 (AIO KRK 0306; FIRE-3).
Cancers 14.22. Nov. 2022. DOI
EMT-Related Genes Have No Prognostic Relevance in Metastatic Colorectal Cancer as Opposed to Stage II/III: Analysis of the Randomised, Phase III Trial FIRE-3 (AIO KRK 0306; FIRE-3).
Cancers 14.22. Nov. 2022. DOI
[11]
C. A. Scholbeck • H. Funk • G. Casalicchio
Algorithm-Agnostic Interpretations for Clustering.
Preprint (Sep. 2022). arXiv
Algorithm-Agnostic Interpretations for Clustering.
Preprint (Sep. 2022). arXiv
[10]
C. Fritz • G. De Nicola • M. Rave • M. Weigert • Y. Khazaei • U. Berger • H. Küchenhoff • G. Kauermann
Statistical modelling of COVID-19 data: Putting generalized additive models to work.
Statistical Modelling 24.4. Aug. 2022. DOI
Statistical modelling of COVID-19 data: Putting generalized additive models to work.
Statistical Modelling 24.4. Aug. 2022. DOI
[9]
M. Mittermeier • M. Weigert • D. Rügamer • H. Küchenhoff • R. Ludwig
A deep learning based classification of atmospheric circulation types over Europe: projection of future changes in a CMIP6 large ensemble.
Environmental Research Letters 17.8. Jul. 2022. DOI
A deep learning based classification of atmospheric circulation types over Europe: projection of future changes in a CMIP6 large ensemble.
Environmental Research Letters 17.8. Jul. 2022. DOI
[8]
A. Bauer
Flexible approaches in functional data and age-period-cohort analysis with application on complex geoscience data.
Dissertation LMU München. Jun. 2022. DOI
Flexible approaches in functional data and age-period-cohort analysis with application on complex geoscience data.
Dissertation LMU München. Jun. 2022. DOI
[7]
A. Bauer • M. Weigert • H. Jalal
APCtools: Descriptive and Model-based Age-Period-Cohort Analysis.
The Journal of Open Source Software 7.73. May. 2022. DOI
APCtools: Descriptive and Model-based Age-Period-Cohort Analysis.
The Journal of Open Source Software 7.73. May. 2022. DOI
[6]
W. Hartl • P. Kopper • A. Bender • F. Scheipl • A. G. Day • G. Elke • H. Küchenhoff
Protein intake and outcome of critically ill patients: analysis of a large international database using piece-wise exponential additive mixed models.
Critical Care 26.7. Jan. 2022. DOI
Protein intake and outcome of critically ill patients: analysis of a large international database using piece-wise exponential additive mixed models.
Critical Care 26.7. Jan. 2022. DOI
2021
[5]
M. Mittermeier • M. Weigert • D. Rügamer
Identifying the atmospheric drivers of drought and heat using a smoothed deep learning approach.
Tackling Climate Change with ML @NeurIPS 2021 - Workshop on Tackling Climate Change with Machine Learning at the 35th Conference on Neural Information Processing Systems. Virtual, Dec 06-14, 2021. PDF
Identifying the atmospheric drivers of drought and heat using a smoothed deep learning approach.
Tackling Climate Change with ML @NeurIPS 2021 - Workshop on Tackling Climate Change with Machine Learning at the 35th Conference on Neural Information Processing Systems. Virtual, Dec 06-14, 2021. PDF
[4]
A. Bauer • F. Scheipl • H. Küchenhoff
Registration for Incomplete Non-Gaussian Functional Data.
Preprint (Aug. 2021). arXiv
Registration for Incomplete Non-Gaussian Functional Data.
Preprint (Aug. 2021). arXiv
[3]
A. M. Keppler • K. Küßner • A.-L. Schulze • E. M. Suero • C. Neuerburg • M. Weigert • C. Braun • W. Böcker • C. Kammerlander • C. Zeckey
Radiographic cortical thickness parameters as predictors of rotational alignment in proximal tibial shaft fractures: a cadaveric study.
BMC Musculoskeletal Disorders 22.590. Jun. 2021. DOI
Radiographic cortical thickness parameters as predictors of rotational alignment in proximal tibial shaft fractures: a cadaveric study.
BMC Musculoskeletal Disorders 22.590. Jun. 2021. DOI
[2]
M. Weigert • A. Bauer • J. Karl • A. Nalmpatian • H. Küchenhoff • J. Schmude
Semiparametric APC analysis of destination choice patterns: Using generalized additive models to quantify the impact of age, period, and cohort on travel distances.
Tourism Economics 28.5. Jan. 2021. DOI
Semiparametric APC analysis of destination choice patterns: Using generalized additive models to quantify the impact of age, period, and cohort on travel distances.
Tourism Economics 28.5. Jan. 2021. DOI
2020
[1]
J. Wrobel • A. Bauer • J. McDonnel • F. Scheipl
registr: Curve Registration for Exponential Family Functional Data. R package.
2020. GitHub
registr: Curve Registration for Exponential Family Functional Data. R package.
2020. GitHub
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2024-12-27 - Last modified: 2026-01-02