This thesis focuses on improving the reliability and trustworthiness of machine learning, particularly in unsupervised learning methods like manifold learning. It investigates the challenges of evaluating manifold learning techniques and proposes improvements for embedding evaluation, outlier detection, and cluster analysis, using methods like UMAP and DBSCAN. Additionally, the thesis contributes to supervised learning by presenting a benchmark study on survival prediction in multi-omics cancer data and exploring the effects of design and analysis choices on benchmark results. (Shortened).
BibTeXKey: Her22