Avoiding C-Hacking When Evaluating Survival Distribution Predictions With Discrimination Measures

MCML Authors

Andreas Bender

Dr.

→ Group Bernd Bischl
 Statistical Learning and Data Science

Abstract

Motivation: In this article, we consider how to evaluate survival distribution predictions with measures of discrimination. This is non-trivial as discrimination measures are the most commonly used in survival analysis and yet there is no clear method to derive a risk prediction from a distribution prediction. We survey methods proposed in literature and software and consider their respective advantages and disadvantages.<br>Results: Whilst distributions are frequently evaluated by discrimination measures, we find that the method for doing so is rarely described in the literature and often leads to unfair comparisons or ‘C-hacking’. We demonstrate by example how simple it can be to manipulate results and use this to argue for better reporting guidelines and transparency in the literature. We recommend that machine learning survival analysis software implements clear transformations between distribution and risk predictions in order to allow more transparent and accessible model evaluation.

article SBV22

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Bioinformatics

38.17. Sep. 2022.

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Authors

R. Sonabend • A. Bender • S. Vollmer

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Links

DOI GitHub

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Research Area

 A1 | Statistical Foundations & Explainability