Learned Image Compression for HE-Stained Histopathological Images via Stain Deconvolution

MCML Authors

Peter Schüffler

Prof. Dr.

Core PI

Computational Pathology

Abstract

Processing histopathological Whole Slide Images (WSI) leads to massive storage requirements for clinics worldwide. Even after lossy image compression during image acquisition, additional lossy compression is frequently possible without substantially affecting the performance of deep learning-based (DL) downstream tasks. In this paper, we show that the commonly used JPEG algorithm is not best suited for further compression and we propose Stain Quantized Latent Compression (SQLC), a novel DL based histopathology data compression approach. SQLC compresses staining and RGB channels before passing it through a compression autoencoder (CAE) in order to obtain quantized latent representations for maximizing the compression. We show that our approach yields superior performance in a classification downstream task, compared to traditional approaches like JPEG, while image quality metrics like the Multi-Scale Structural Similarity Index (MS-SSIM) is largely preserved.

inproceedings FNW+24

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MOVI @MICCAI 2024

2nd International Workshop on Medical Optical Imaging and Virtual Microscopy Image Analysis at the 27th International Conference on Medical Image Computing and Computer Assisted Intervention. Marrakesh, Morocco, Oct 06-10, 2024.

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Authors

M. Fischer • P. Neher • T. Wald • S. Dias Almeida • S. Xiao • P. J. Schüffler • R. Braren • M. Götz • A. Muckenhuber • J. Kleesiek • M. Nolden • K. Maier-Hein

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Links

DOI GitHub

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Research Area

 C1 | Medicine